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GLUTABIANE 600 mg contains glutathione, a vital antioxidant that plays a key role in detoxification and cellular defense mechanisms. It has been widely used via intravenous administration in cases of acute poisoning and chronic liver disorders. Recent research has explored its oral therapeutic potential, particularly in managing nonalcoholic fatty liver disease (NAFLD).
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✅ Description:
- In a multicenter, open-label pilot study (Trial ID: UMIN000011118), oral glutathione was evaluated in patients with ultrasonography-confirmed NAFLD.
- Initial Phase (3 months): All participants underwent lifestyle modifications (diet and exercise).
- Treatment Phase (4 months): Patients received oral glutathione at 300 mg/day.
Key Findings:
Significant reduction in ALT levels, indicating improved liver function.
Reduction in triglycerides (TG), non-esterified fatty acids (FFA), and ferritin.
Younger patients and those without advanced diabetes responded better.
Improvements were observed in liver fat content, measured via controlled attenuation parameter (CAP).
These results suggest the potential efficacy of oral glutathione in improving liver function and metabolic markers in NAFLD. Further large-scale studies are recommended.
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✔️ Benefits:
- Helps manage metabolic syndrome and supports weight loss
- Reduces triglyceride and fatty acid accumulation in the liver
- Enhances insulin sensitivity and stabilizes blood glucose levels
- Suppresses inflammatory cytokines: TNF-α, IL-1, IL-6
- Boosts mitochondrial energy production
- Regulates adiponectin and leptin, essential for fat metabolism
- Lowers oxidative stress and lipid peroxidation (MDA)
- Inhibits activation of Kupffer cells, hepatic stellate cells (HSCs), and collagen production in liver fibrosis
✔️ Dosage & Administration
- Recommended Dose: 2 capsules per day
- Duration: For best results, use continuously for 3 months
- Administration: Oral use, preferably with meals
✔️ Storage Conditions
- Store in a cool, dry place away from direct sunlight and moisture
- Keep out of reach of children
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